SENS Research Foundation

La fondation SENS (Strategies for Engineered Negligible Senescence) créée par les transhumanistes Aubrey de Grey et David Gobel en 2009 et basée a Mountain View (San Jose, CA) s’intéresse a la question de la médecine régénérative. Leur challenge: déjouer les causes du vieillissement par la régénération de tissus cellulaires.

Au menu: Defeat Aging, 3D Bioprinting, Apoptosis, Cancer, Stem Cells.
http://sens.org/research/grant-submission-process
Voir aussi Methuselah Foundation et Calico.

Centenarians

« Studies have consistently shown that lifestyle factors have little to do with their remarkable longevity; something’s clearly going on at the genetic level. »

In the affiliation of Aubrey de Grey’s researchs on defeating aging, this article written by George Dvorsky and inspired by Andy Coghlan’s article (Somatic mutations found in the healthy blood compartment of a 115-yr-old woman demonstrate oligoclonal hematopoiesis) highlines the link between blood and stem cells in the aging process:

« This is all quite exciting because it hints at a very plausible rejuvenation therapy. Conceivably, we could re-inject ourselves with stem cells saved from birth or early life — stem cells free from mutations and with full-length telomeres. Now, this wouldn’t halt the aging process, but it could have a dramatic impact on our health and the rate at which we age. Hmmm, this recent breakthrough suddenly seems all that more pertinent. »

 

Article George Dvorsky, 2014.
Article Andy Coghlan: Genome Res.-2014-Holstege-gr.162131.113
Article George Dvorsky ‘could reinject, 2012 .
Article Ruckh, and al « Rejuvenation of Regeneration in the Aging Central Nervous System », 2011.
Article  Suzanne Young, May 9, 2014 « Can Compounds in Young Blood Fix Aging? »